Near infrared spectroscopic transmittance measurements for pharmaceutical powder mixtures
نویسندگان
چکیده
منابع مشابه
Near-Infrared-Spectroscopic Investigations of Solid Pharmaceutical Formulations
In this study near-infrared (NIR) transmission and diffuse reflection spectra of tablets with two different pharmaceutical active substances in variable concentrations were recorded. The purpose of these tests was to correlate the spectra with the content of active ingredient, hardness and moisture content in order to implement a fast, non-destructive quality control of solid drug formulations ...
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Fusing complex data from two disparate sources has been demonstrated to improve the accuracy in quantifying active ingredients in mixtures of pharmaceutical powders. A four-component simplex-centroid design was used to prepare blended powder mixtures of acetaminophen, caffeine, aspirin and ibuprofen. The blends were analyzed by Fourier transform infra-red spectroscopy (FTIR) and powder X-ray di...
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We have set up a novel direct detection system to measure filter transmittances over an attenuation range of at least 5 decades, with relative combined standard uncertainties as low as 0.5% (1σ) per decade, in the 9 μm to 11 μm spectral region. This system, using an apparatus originally designed for a heterodyne measurement of transmittance, achieves higher accuracy at the expense of a reduced ...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical and Biomedical Analysis
سال: 2016
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2016.02.006